If you’re on a GLP-1 medication, you already know how powerful it can be for managing weight and appetite. But you’ve probably noticed it comes with a few bumps in the road, too, especially when it comes to digestion and regularity. That’s where prebiotic fiber can make a big difference. Let’s break it down. What Is Prebiotic Fiber? Prebiotic fiber is a type of fiber your body can’t digest, but the good bacteria in your gut can. Think of it as food for the healthy bacteria in your digestive system. When those good bacteria get the fuel they need, they thrive, multiply, and help keep your gut balanced and functioning properly. Unlike probiotics, which add more bacteria to your gut, prebiotics nourish the good bacteria you already have. How Does Prebiotic Fiber Help the Body? Here’s what makes prebiotic fiber so valuable: Supports Healthy Digestion Prebiotic fiber helps keep things moving smoothly in your digestive tract, promoting regularity and reducing common issues like constipation. Feeds Good Gut Bacteria By serving as a food source for beneficial bacteria such as Akkermansia muciniphila and Faecalibacterium prausnitzii, prebiotics help maintain a balanced gut microbiome, which is associated with reduced inflammation and improved overall health. Supports Natural GLP-1 Activation Some fibers, like the blend in our new GLP-ONE Support Gut Health Booster Prebiotic Fiber Powder, can naturally support the body’s release of GLP-1 hormones, helping to control appetite, support blood sugar balance, and promote fullness between meals.* Improves Gut Barrier Strength When prebiotic fibers are broken down by the good bacteria in your gut, they produce short-chain fatty acids like butyrate. These help strengthen the gut lining, keeping it healthy and better able to block out harmful bacteria and toxins. May Support Metabolic Health A healthy gut microbiome, supported by prebiotic fiber, has been linked to improved metabolic markers, including better blood sugar control and appetite regulation. Why People on GLP-1 Medications Need More Fiber GLP-1 receptor agonists, commonly prescribed for weight management and type 2 diabetes, work by slowing gastric emptying, which helps increase feelings of fullness. However, this delayed digestion can lead to side effects such as constipationand bloating.1 That’s where fiber comes in. Fiber plays a critical role in digestive health by keeping things moving smoothly, nourishing your gut bacteria, and supporting regularity. Without enough of it, your digestive system can get sluggish, especially when paired with medications that naturally slow digestion. If you’re on a GLP-1 medication, your need for fiber is even greater to help offset slower digestion and keep your gut microbiome in balance. Incorporating prebiotic fiber into the diet can help mitigate these side effects by promoting regular bowel movements and supporting a healthy gut microbiome. Additionally, certain prebiotic fibers may enhance the body's natural GLP-1 secretion, further supporting appetite control and blood sugar regulation.2 Fiber Intake: A Common Nutritional Gap The problem? Most people aren’t getting nearly enough fiber. Despite its importance, fiber intake among US adults is significantly below recommended levels. The average daily intake is approximately 16 grams, whereas the USDA recommends 25 grams per day for women and 38 grams per day for men.3 Signs you might need more fiber: Constipation or irregular bowel movements Bloating and digestive discomfort Trouble feeling satisfied between meals Low intake of fruits, vegetables, and whole grains Adding a targeted prebiotic fiber supplement can be a simple, effective way to help meet your daily fiber needs, support gut health, and feel more comfortable—whether you’re navigating a weight loss journey on GLP-1 medication or simply looking to improve your overall digestive health.* Conclusion Prebiotic fiber plays a vital role in maintaining digestive health, supporting beneficial gut bacteria, and potentially enhancing the effects of GLP-1 medications. Considering the widespread deficiency in fiber intake, especially among those on GLP-1 therapies, incorporating prebiotic-rich foods or supplements can be a beneficial strategy for overall health and well-being. Shop our GLP-ONE Support Collection today! References 1. Jalleh RJ et al. J Clin Endocrinol Metab. 2024;110(1):1-15.2. Bevilacqua A et al. Foods. 2024;13(3):446.3. Bliss R. USDA. 2015. Accessed on May 14, 2025, from https://www.usda.gov/about-usda/news/blog/online-nutrition-resources-your-fingertips.