Bone Health

9 Nutrients That Support Brain and Bone Health Through Weight Loss and Aging

9 Nutrients That Support Brain and Bone Health Through Weight Loss and Aging

Aging well isn’t just about appearance—it’s about feeling strong, thinking clearly, and maintaining independence. Two of the most important systems to support as we age are our bones and our brains. The good news? Many of the nutrients that support bone strength can also help maintain cognitive health.

Whether you’re navigating midlife, recovering from weight loss surgery, or using a GLP-1 medication, this guide offers a foundation to help you feel your best—from the inside out.

Why Bone Health Matters More Than You Think

As we age, bone loss becomes more common—especially for postmenopausal women and individuals who’ve experienced significant weight loss. Weakened bones can increase the risk of fractures, poor posture, and reduced mobility.1

The right combination of targeted nutrients and regular physical activity can help support healthy bone density for years to come.

Why Brain Health Deserves Daily Attention

Forgetfulness isn't inevitable. Supporting your brain through nutrition may help preserve memory, focus, and cognitive function. Factors such as chronic inflammation, nutrient deficiencies, and reduced blood flow can all contribute to cognitive decline—and many of these are modifiable through diet and lifestyle.2

Nine Key Nutrients That Support Both Brain and Bone Health

1. Calcium (citrate form)

  • Supports: Bone strength
  • Why it matters: Most adults need 1,200-1,500mg/day, particularly after weight loss surgery. Calcium citrate is often recommended for better absorption, especially for bariatric patients.

2. Vitamin D3

  • Supports: Calcium absorption | cognitive health
  • Why it matters: Many adults, including those who have undergone bariatric surgery, are deficient in vitamin D. D3 helps maintain bone mineralization and may play a role in supporting healthy brain function.

3. Vitamin K2 (MK-7)

  • Supports: Directs calcium to bones | vascular and brain health
  • Why it matters: Vitamin K2 helps guide calcium into bones and away from soft tissues like arteries. Early research suggests it may also benefit brain health by supporting vascular integrity.3

4. Magnesium

  • Supports: Bone density | brain signaling and sleep
  • Why it matters: Magnesium plays a role in over 300 biochemical reactions in the body—including muscle and nerve function, mood regulation, and calcium metabolism.

5. Omega-3 Fatty Acids (EPA/DHA)

  • Support: Brain structure | bone health
  • Why they matter: Omega-3s are widely recognized for their role in supporting cognitive health. Some studies suggest they may also help reduce bone loss and support joint health.4

6. B Vitamins (B6, B12, Folate)

  • Support: Mental clarity and mood | bone support
  • Why they matter: These vitamins help regulate homocysteine, a compound that has been linked to both brain and bone concerns when elevated. Deficiencies are also common after bariatric surgery.

7. Protein

  • Supports: Bone matrix | neurotransmitter production
  • Why it matters: Protein is essential for maintaining lean body mass and supporting neurotransmitter function. It’s also a building block for bones and muscles—especially important as we age.

8. Choline

  • Supports: Memory | cellular structure
  • Why it matters: Choline plays a key role in learning, memory, and healthy cell membranes. Many people don’t get enough of this essential nutrient through food alone.

9. Antioxidants (Vitamins C, E, and polyphenols)

  • Support: Oxidative stress protection | collagen formation
  • Why they matter: Antioxidants help reduce inflammation and protect tissues from damage. Vitamin C also supports collagen formation, a key structural component in both bones and skin.5

Bottom Line

As we age—or navigate changes like weight loss surgery or GLP-1 use—supporting both brain and bone health becomes even more important. With the right nutrients, you can stay strong, sharp, and independent at every stage. From calcium and vitamin D to omega-3s and B vitamins, targeted nutrition can make a meaningful difference in how you feel and function through the years.

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References

1. Sözen T et al. Eur J Rheumatol. 2017;4(1):46-56.
2. Kuhn HG et al. Cereb Circ Cogn Behav. 2024;6:100217.
3. Roumeliotis S et al. Front Aging Neurosci. 2025;16:1527535.
4. Orchard TS et al. Br J Nutr. 2012;107 Suppl 2(0 2):S253-260.
5. Lobo V et al. Pharmacogn Rev. 2010;4(8):118-126.

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